Synthesis Paper for PICOT question.

I’m trying to study for my Nursing course and I need some help to understand this question.

Assignment Directions: Synthesis Paper

Below you will find the required elements of this assignment. All submissions must be in APA format. Please note there is a minimum of 1200 words, or 4 full pages for this assignment. Points will be deducted for not adhering to the word count.

  • Abstract: on one page (less than 200 words), and includes the clinical problem, the objective or purpose of the paper, search engines & key words used, specific results, and conclusion.Hint: Review the abstract in one of the studies you located.The information in your paper should be similar in terms of content and format.
  • Introduction: Succinctly identify the clinical problem that requires an evidence-based solution. You may use systematic reviews, meta-analyses, or Cochrane reviews to document the significance of the topic in the introduction only. End the introduction with your PICOT question. You may refer to the Literature Table in this section.
  • Body/Content: (Use the bolded words below as headings)
    • Literature Search: Identify the databases that were used to search for the relevant literature (CINAHL, PubMed, etc.) and the key terms used.Be sure to include at least 3 sentences in all paragraphs.
    • Literature Review: Use a minimum of 3 peer reviewed, primary RCTs and one clinical guideline that informs the question. If there is no clinical guideline, find a 4th RCT.
      • You must use randomized controlled trials ONLY (systematic reviews or meta-analyses are not allowed in the literature review) [were the participants randomly placed into a control or intervention group?If not, then it is NOT an RCT].
      • If not already completed, create a literature table(see below) to summarize these key points, which will help you write this section. The table should be appended to the end of the paper.
      • Concisely summarize each RCT, writing a succinct paragraph stating the purpose, method/procedure, sample, measures, and specific results as they relate to the PICOT.
      • At the end of each paragraph that discusses the respective RCT, after discussing all aspects of the study (see previous bullet point), use the ‘RCT Appraisal Checklist’ to appraise the strengths and weaknesses of the study. All nine components of the ‘RCT Appraisal Checklist’ must be included in the strengths and weaknesses discussion.Do NOT include the authors’ review of literature.
      • Summarize the recommendations of the clinical guideline as it relates to the proposed practice change/PICOT.
    • Synthesis: synthesize the research findings from all studies and the guideline, always relating them back to your PICOT question. The first paragraph should be a concise restatement of each study’s results, including statistics and a citation. Summarize the guideline recommendation. The second paragraph should be the “meat” of the synthesis where you describe similarities and differences among the study results, how the results impact the proposed practice change/EBP project, as well as what is known and not known (gaps) in the field for future research. Be concise.
    • Clinical recommendations: Given the synthesis of the literature, what clinical recommendations emerge for your clinical setting / population? Describe how practice must change to become evidence-based.
  • Reference list (does not count towards word count).
  • Table: see template on next page. Label the table and refer to it in the body of the paper using APA formatting for table usage (does not count towards word count). While the paper should appear in portrait/vertical position, the lit table should appear in the landscape/horizontal position.

Table 1

Literature Review


(in APA without indention)


Design and Measures (relevant to PICOT topic)


(total size [N], control/intervention size [n], demographics relevant to PICOT topic)

Outcomes / statistics

(include significant findings related to the PICOT topic & include p-values or confidence intervals)

McCain, G.C., Del Moral, T., Duncan, R. C., Fontaine J. L., & Pino, L. D. (2012). Transition from gavage to nipple feeding for preterm infants with bronchopulmonary dysplasia. Nursing Research, 61(6), 360-397.

To test the hypothesis that preterm infants with bronchopulmonary dysplasia (BPD) who transitioned from gavage to nipple feeding in the semi-demand method would achieve nipple feeding sooner and be discharged from the hospital sooner than control infants who received standard care.

Design:Randomized controlled trial (RCT)


  • Days to full nipple feedings
  • Length of stay (LOS)
  • Preterm infants (N=86) < 34 weeks’ gestation
  • Control group (n=42)
  • Intervention group (n=44)
  • All participants were <2,000 grams in weight, < 34 weeks gestation, male or female, with BPD, and were Caucasian or Black

Experimental infants achieved full nipple feeds sooner than control infants (p< .0001); LOS was five days shorter in experimental infants, but was not statistically significant.

Delete sample row above before submitting Lit Table








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